Ressource pédagogique : Sarcoma Database: a unique tool for research on mesenchymal tumors

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Description (résumé)

Clinical biology session The main sarcoma databases are the Conticabase (https://conticabase.sarcomabcb.org) and the ConticaGist (https://conticagist.sarcomabcb.org) with 18000 patients and which collect data describing patient, primary tumor, histology, molecular biology, treatment and follow-up as well as the material stored (paraffin blocks, frozen tissue, peripheral blood and cell lines). With the organization of national networks, data on practices regarding histological diagnosis and clinical management are collected in specific databases (https://rreps.sarcomabcb.org and https://netsarc.sarcomabcb.org). Currently, this database contents data from 45000 patients and will be soon merge with the Conticabase and ConticaGist. These databases allow studies on medical practices, medico-economical studies, description of large cohorts, pathological and molecular studies, such as histological and molecular grading, and basic research studies such as the full genome sequencing in leiomyosarcomas in the context of the ICGC programme. We now have the project to integrate heterogeneous data, such as genomic, expression profiling and NGS data with the phenotypic data of the sarcomaBCB in the open source platforms I2B2 and Transmart in order to make available to the clinicians a tool for the best selection of targeted treatment for homogeneous groups of patients and to the researchers a tool for their research projects. Cette présentation a été donnée dans le cadre du BRIO SIRIC scientific day 3 organisé annuellement par le SIRIC BRIO et qui a pour but de réunir tous les acteurs du SIRIC BRIO et plus largement de la cancérologie à Bordeaux.

"Domaine(s)" et indice(s) Dewey

• Cancer (616.994)

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