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<title><string language="fre"><![CDATA[Dr Raphaël Duivenvoorden - Trained Immunity as a novel therapeutic strategy]]></string></title>
<language>ENG</language>
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<string language="fre"><![CDATA[Innate immune
cells form a vital first line of defense against pathogens, and their
activation upon recognition of pathogens is rapid and non-specific. For a long
time it has been assumed that innate immune cells do not develop immunological
memory. However, over the past years this view has been challenged. A new
concept has emerged, referred to as trained immunity. Upon stimulation of
innate immune cells, long-term functional and epigenetic reprogramming can
occur. Although the cells return to a non-activated state after the initial
stimulus, they develop an enhanced secondary response to a subsequent
non-specific stimulus. This shows that the innate immune system exhibits
adaptive characteristics, which may have evolved to provide greater protection against
reinfection. In this presentation we will reflect on the concept and underlying
immunological mechanisms of trained immunity and discuss how trained immunity
can be utilized as a therapeutic strategy to prevent infection and potentially
treat other immune related diseases.
 ]]></string></description>
<keyword><string language="fre"><![CDATA[immunité]]></string></keyword><keyword><string language="fre"><![CDATA[pathologie des poumons]]></string></keyword>
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<date><dateTime>2020-09-25</dateTime></date>
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<string language="fre"><![CDATA[Droits réservés à l'éditeur et aux auteurs. 
]]></string>
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<string language="fre"><![CDATA[LE STUDIUM Conferences]]></string>
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<string language="fre"><![CDATA[Novel host- and microbiota-directed strategies for treating respiratory infections]]></string>
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<string language="fre"><![CDATA[Maladies des poumons (hypertension artérielle pulmonaire, hypertension pulmonaire, maladie obstructive respiratoire chronique, maladies respiratoires, ouvrages généraux sur les maladies des bronches et des poumons)]]></string>
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