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<title><string language="fre"><![CDATA[Dr Magdalena Malinowska - Grape cane extracts a natural ingredients with cosmetic activities]]></string></title>
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<string language="fre"><![CDATA[Modern and
effective skin care formulations based on a natural ingredients has become the
key issue in cosmetic industry. It is well known, that grapes are a rich source
of many valuable compounds like E-resveratrol,
which exhibits several biological activities for health and beauty. Wine
production process generates various biomolecule-rich by-products including
pomace, leaves or canes. It creates an opportunity to the exploitation of these
natural resources of metabolites in cosmetic formulations. In our studies, we
focused on the polyphenolic profiles of unique grape varieties, cultivated in
the Loire Valley in France, which over the past decades became extremely rare. The
metabolomic screening of the tested grape
extracts involved the analysis and data integration of
all the metabolites, based on high-throughput, multivariate data. Basing on the
results obtained, we evaluated the cosmetic potential
of the selected grape varieties as the multifunctional rejuvenating agents.
These sources of grape metabolites exhibit various biological activities
including skin whitening potential, strong antioxidant activity and the
delaying of cellular senescence. The confirmed biological effect was
additionally supplemented with the evaluation of the bioavailability and skin
permeability of the extracts key metabolites. Importantly, the results allowed
for the initiation of in vitro cell
cultures of the selected rare grape varieties for their future utilisation in
innovative skin care formulations.
 ]]></string></description>
<keyword><string language="fre"><![CDATA[cosmétique]]></string></keyword><keyword><string language="fre"><![CDATA[resveratrol]]></string></keyword><keyword><string language="fre"><![CDATA[ingrédients naturels]]></string></keyword>
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<date><dateTime>2020-12-03</dateTime></date>
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