31793 résultats

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31793 résultats
page 3049 sur 3180
résultats 30481 à 30490
Canal-U
Description : Crystal (Cry) proteins from Bacillus thuringiensis are used as effective insecticides. These pore forming toxins act within the midgut of insects killing them. Cry5B, has been found to target and kill intestinal parasitic nematodes including Ascaris suum. Cry5B forms pores in the nematode intestines ...
Mots clés : ascaris
Date : 29-11-2021
Droits : Droits réservés à l'éditeur et aux auteurs.
Canal-U
Description : The intestine of nematode parasites is involved in more than digestion, absorption and storage of nutrients. It is involved in vesicular trafficking, ageing, innate immunity, drug metabolism and excretion making it a sensitive tissue for drugs to target. We used Fluo-3 AM, a calcium sensitive dye ...
Mots clés : ascaris
Date : 29-11-2021
Droits : Droits réservés à l'éditeur et aux auteurs.
Canal-U
Description : The interaction of the macrocyclic lactones with P-glycoprotein have been well-characterized in different ascarids and have been implicated in drug resistance. While adult stages of the canine ascarid Toxocara canis do not exhibit resistance, somatic larvae have been tolerant of the macrocyclic ...
Mots clés : toxoplasmose
Date : 29-11-2021
Droits : Droits réservés à l'éditeur et aux auteurs.
Canal-U
Description : To monitor and evaluate mass drug administration (MDA) programs for soil-transmitted helminths (STHs) the diagnostic standard is the microscopic detection of STH specific eggs in stool smears (Kato- Katz). However, this technique has major drawbacks resulting in a pressing need for improved diagnostic ...
Mots clés : ascaris
Date : 29-11-2021
Droits : Droits réservés à l'éditeur et aux auteurs.
Canal-U
Description : Ascaris suum affects feed conversion and weight gain of pigs, but effects on intestinal microbiota remain largely unexplored. Therefore, the intestinal microbiome and metabolome was assessed in pigs that were infected once with 10,000 A. suum eggs as well as pigs that received a trickle-infection ...
Mots clés : ascaris
Date : 29-11-2021
Droits : Droits réservés à l'éditeur et aux auteurs.
Canal-U
Description : Toxocara canis and Toxocara cati are worldwide-distributed zoonotic intestinal helminths with frequent exposure to humans in which they can cause severe disease pathology. Upon infection, initial recognition of pathogens is mediated by pattern recognition receptors (PRRs), of which myeloid C-type lectin ...
Mots clés : toxoplasmose
Date : 29-11-2021
Droits : Droits réservés à l'éditeur et aux auteurs.
Canal-U
Description : Ascarid parasites cause a massive burden on people in the developing world and on veterinary animals worldwide. We use a limited arsenal of anthelmintics to treat these infections. As the use of anthelmintics increases, resistance to these compounds increases. Across diverse parasitic nematode s ...
Mots clés : ascaris
Date : 30-11-2021
Droits : Droits réservés à l'éditeur et aux auteurs.
Canal-U
Description : Ligand-gated ion channels provide an excellent test for any expression system and for C. elegans as a model for parasitic nematode species, including the ascarids. They are complex proteins made of multiple subunits which are encoded by a large gene family, that carry multiple post-translational ...
Mots clés : ascaris
Date : 30-11-2021
Droits : Droits réservés à l'éditeur et aux auteurs.
Canal-U
Description : Despite their large diversity, most of the nematode species are susceptible to broad spectrum anthelmintics. In that respect, it is tempting to speculate that extensive C. elegans data about molecular anthelmintic targets could lay strong basis to investigate their counterparts in phylogenetically distantly ...
Mots clés : ascaris
Date : 30-11-2021
Droits : Droits réservés à l'éditeur et aux auteurs.
Canal-U
Description : This presentation will provide an overview on recent investigations concerning the P-glycoprotein gene family in the equine roundworm Parascaris univalens. As prominent members of the ATP-Binding-Cassette (ABC) transmembrane transporters, Pgps are considered to play an important role in the expulsion ...
Mots clés : parasite
Date : 30-11-2021
Droits : Droits réservés à l'éditeur et aux auteurs.